Can Aging Be Reversed? David Sinclair on Longevity Science

Podcast: David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!

Guest: David Sinclair

Published: March 23, 2026

Topics: David Sinclair, reverse aging, longevity science, epigenetic clock, NAD, sirtuins, cellular rejuvenation, anti-aging diet, hormesis, Information Theory of Aging

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Section Division Analysis

Introduction and Motivation: This section covers David Sinclair's personal story about his grandmother, his core philosophy of rejecting aging as natural and acceptable, and the initial framing of his work. The Breakthrough Technology and First Human Trials: This section details the specific technology of using three genes to reverse aging, its application in mice, and the upcoming first-in-human trials to cure blindness. 3....

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David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!

David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!

Featuring: David Sinclair

Listen to Original Episode

Summary

Section Division Analysis

  1. Introduction and Motivation: This section covers David Sinclair's personal story about his grandmother, his core philosophy of rejecting aging as natural and acceptable, and the initial framing of his work.
  2. The Breakthrough Technology and First Human Trials: This section details the specific technology of using three genes to reverse aging, its application in mice, and the upcoming first-in-human trials to cure blindness. 3....

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